Structure of Heparin Sodium (representative subunits): The potency is determined by a biological assay using a USP reference standard based on units of heparin activity per milligram. In heparin sodium, the acidic protons of the sulfate units are partially replaced by sodium ions. Heparin is strongly acidic because of its content of covalently linked sulfate and carboxylic acid groups. These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5), and are joined by glycosidic linkages, forming polymers of varying sizes. Although others may be present, the main sugars occurring in heparin are: (1) α- L-iduronic acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose-6-sulfate, (3) β-D-glucuronic acid, (4) 2-acetamido-2-deoxy-α-D-glucose, and (5) α-L-iduronic acid. Heparin Sodium, USP is a heterogenous group of straight-chain anionic mucopolysaccharides, called glycosamino-glycans having anticoagulant properties. Heparin sodium in the ADD-Vantage™ system is intended for intravenous administration only after dilution. When smaller doses are required, the unused portion should be discarded. The solution contains no bacteriostat, antimicrobial agent or added buffer and is intended for use only as a single-dose injection. May contain sodium hydroxide and/or hydrochloric acid for pH adjustment. Each container contains 10000, 12500, 20000 or 25,000 USP Heparin Units 40 or 80 mg sodium chloride added to render isotonic (see HOW SUPPLIED section for various sizes and strength). Heparin Sodium Injection, USP is a sterile, nonpyrogenic solution of heparin sodium (derived from porcine intestinal mucosa) in water for injection. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Heparin. Tell the doctor if you have any side effect that bothers you or that does not go away. The most common side effects of Heparin include: Get medical help right away, if you have any of the symptoms listed above. skin changes where the medication was injected,.coughing up blood or vomit that looks like coffee grounds,.dark or blue-colored skin on your hands or feet,.severe pain or swelling in your stomach, lower back or growing,.Heparin may cause serious side effects including: What are the possible side effects of Heparin? Heparin belongs to a class of drugs called Anticoagulants, Cardiovascular, Anticoagulants, Hematologic.Heparin may be used alone or with other medications. Heparin is a prescription medicine used to treat and prevent the symptoms of blood clots caused by medical conditions or medical procedures. Find Lowest Prices on What is Heparin and how is it used?
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